2-(Bromomethyl)acrylic acid ethyl ester
[CAS 17435-72-2]

Identification

• Classification: Chemical reagent >> Organic reagent >> Ester >> Ethyl ester compound
• Name: 2-(Bromomethyl)acrylic acid ethyl ester
• Synonyms: 2-(Bromomethyl)-2-propenoic acid ethyl ester; 2-Carbethoxyallyl bromide; Ethyl 2-(bromomethyl)acrylate; Ethyl 2-(bromomethyl)propenoate; Ethyl 3-bromo-2-(methylene)propanoate; Ethyl 3-bromo-2-methylenepropionate; Ethyl bromomethacrylate
• Molecular Formula: C₆H₉BrO₂
• Molecular Weight: 193.04
• CAS Registry Number: 17435-72-2
• EC Number: 628-033-1
• SMILES: CCOC(=O)C(=C)CBr

Properties

• Density: 1.4±0.1 g/cm³ Calc.^*, 1.398 g/mL (Expl.)
• Melting point: 134-136 °C (Expl.)
• Boiling point: 191.9±23.0 °C 760 mmHg (Calc.)^*, 238.5 °C (Expl.)
• Flash point: 69.9±22.6 °C (Calc.)^*, 81 °C (Expl.)
• Index of refraction: 1.471 (Calc.)^*, Refraction index Data source (Expl.)

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H315-H319-H335
• Safety Statements: P261-P264-P264+P265-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin corrosion	Skin Corr.	1B	H314

chemBlink Chemical Story

Ethyl 2-(bromomethyl)acrylate is an activated unsaturated ester containing both an alpha,beta-unsaturated ester system and a bromomethyl group attached to the alkene. Those two features give synthetic chemists several ways to form new bonds: the bromomethyl carbon can undergo nucleophilic substitution, while the activated double bond can participate in addition and polymer-related chemistry. The ester group also provides a functional handle for later hydrolysis or other transformations. Public exact-CAS information for CAS 17435-72-2 is primarily reagent and synthesis oriented rather than tied to a single commercial product. Its value is therefore best understood as a multifunctional building block whose bromine, alkene, and ester can be addressed selectively in carefully designed reaction sequences.

Exact chemical identity matters because free forms, salts, stereoisomers, hydrates, metabolites, intermediates, and finished products can carry different registry numbers even when their names are closely related. These distinctions affect molecular weight, physical properties, analytical standards, formulation, and interpretation of literature. A reliable chemical database therefore follows the exact substance instead of automatically transferring every property of a related form.

Functional groups are also a map of intended reactivity. Carbonyls, alcohols, amines, halides, alkenes, and heterocycles provide different opportunities for bond formation, while hydrocarbon frameworks influence shape and solubility. In multistep synthesis, the usefulness of an intermediate often comes from being able to transform one position selectively while leaving another group available for a later operation.

Modern chemical development depends as much on characterization as on synthesis. Identity, purity, stereochemistry, water or salt content, and process-related impurities may all need control. Well-characterized intermediates and reference materials therefore matter even when they never become a final commercial product: they make complex manufacturing and research reproducible.

A responsible Chemical Story distinguishes documented use from structural possibility. A familiar molecular scaffold can suggest a hypothesis, but resemblance alone does not establish a biological target, approved indication, or commercial application. When exact-CAS literature is limited, verified chemistry and clearly documented uses are more informative than speculation.

Seen broadly, practical performance emerges from the whole molecular system. Structure, stereochemistry, physical form, synthetic route, reaction environment, and, for biological molecules, metabolism can all determine what a substance actually does. Connecting these details to a documented historical, industrial, or biological role turns a registry entry into a meaningful chemical story.

Exact chemical identity matters because free forms, salts, stereoisomers, hydrates, metabolites, intermediates, and finished products can carry different registry numbers even when their names are closely related. These distinctions affect molecular weight, physical properties, analytical standards, formulation, and interpretation of literature. A reliable chemical database therefore follows the exact substance instead of automatically transferring every property of a related form.

Functional groups are also a map of intended reactivity. Carbonyls, alcohols, amines, halides, alkenes, and heterocycles provide different opportunities for bond formation, while hydrocarbon frameworks influence shape and solubility. In multistep synthesis, the usefulness of an intermediate often comes from being able to transform one position selectively while leaving another group available for a later operation.

Modern chemical development depends as much on characterization as on synthesis. Identity, purity, stereochemistry, water or salt content, and process-related impurities may all need control. Well-characterized intermediates and reference materials therefore matter even when they never become a final commercial product: they make complex manufacturing and research reproducible.

References:
1. Specialist chemical catalogs. CAS 17435-72-2 identity and synthesis use.
2. General organic synthesis literature on bromomethyl acrylate derivatives.

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